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MYLIP Antibody, Biotin Conjugated

MYLIP Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, MYLIP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMYLIP
SpecificityThis is a highly specific antibody against MYLIP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range65-103/445
Subcellular locationCell membrane
SourceKLH conjugated synthetic peptide derived from human MYLIP
Gene ID number29116
Swiss ProtQ8WY64
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activity depends on E2 enzymes of the UBE2D family, Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR, LDLR, Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth, VLDLR and LRP8, E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms MIR IDOL
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMYLIP Conjugated
Short name Conjugated, MYLIP Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, MYLIP (Antibody to)
Alternative techniqueantibodies
Identity 21155
Gene MYLIP
Long gene name myosin regulatory light chain interacting protein
Synonyms name E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor
Locus 6p22, 3
Discovery year 2003-11-26
GenBank acession AF187016
Entrez gene record 29116
Pubmed identfication 10593918 11162443 19688294
RefSeq identity NM_013262
Classification FERM domain containing
Havana BLAST/BLAT OTTHUMG00000016405

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