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MYOG (304CT11.6.1) Monoclonal Antibody

MYOG (304CT11.6.1) Monoclonal Antibody size: 0.1ml 328

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 328
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name1) Monoclonal Antibody, 6, MYOG (304CT11
Also known as1) Monoclonal Antibody, 6, MYOG (304CT11
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMYOG
SpecificityThis is a highly specific antibody against MYOG
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1, 304CT11, 6
SourceThis MYOG antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human MYOG
Gene ID number4656
Swiss ProtP15173
Tested ApplicationsWB
Recommended dilutionsWB(1:1000~4000)
Cross reactivityMouse
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds to the E-box containing (E1) promoter region of the miR-20a gene, Contributes to the atrophy-related gene expression in adult denervated muscles, Cooperates also with myocyte-specific enhancer factor MEF2D and BRG1-dependent recruitment of SWI/SNF chromatin-remodeling enzymes to alter chromatin structure at myogenic late gene promoters, During terminal myoblast differentiation, Essential for the development of functional embryonic skeletal fiber muscle differentiation, Facilitates cell cycle exit during terminal muscle differentiation through the up-regulation of miR-20a expression, However is dispensable for postnatal skeletal muscle growth, Induces fibroblasts to differentiate into myoblasts (By similarity), Plays also a role in preventing reversal of muscle cell differentiation, Required for the recruitment of the FACT complex to muscle-specific promoter regions, Together with MYF5 and MYOD1, cell cycle exit and muscle atrophy, co-occupies muscle-specific gene promoter core regions during myogenesis, phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity, plays a role as a strong activator of transcription at loci with an open chromatin structure previously initiated by MYOD1, thus promoting gene expression initiation, which in turn represses genes involved in cell cycle progression, Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation
Purification method09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Class C basic helix-loop-helix protein 3, MYOG, Myogenic factor 4, Myogenin, bHLHc3, myf-4, MYF4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target1) Monoclonal, 6, MYOG (304CT11
Short name1) Monoclonal Antibody, 6, MYOG (304CT11
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name1) monoclonal (Antibody to), 6, MYOG (304CT11
Alternative techniqueantibodies
Identity 7612
Gene MYOG
Long gene name myogenin
Synonyms gene MYF4
Synonyms gene name myogenin (myogenic factor 4)
Synonyms bHLHc3
Synonyms name myogenic factor 4
Locus 1q32, 1
Discovery year 1990-11-20
GenBank acession BC053899
Entrez gene record 4656
Pubmed identfication 10329008
RefSeq identity NM_002479
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000042127

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