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MYPT1 (Ser507) Antibody, FITC Conjugated

MYPT1 (Ser507) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, MYPT1 (Ser507) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMYPT1 Ser507
SpecificityThis is a highly specific antibody against MYPT1 Ser507
ModificationPhosphorylation
Modification siteSer507
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human MYPT1 around the phosphorylation site of Ser507
Gene ID number4659
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho, Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase, Rho-associated kinase (Rho-kinase), RhoA, Several transcript variants encoding different isoforms have been found for this gene, The guanosine triphosphate(GTP)-bound, The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, Thus, [provided by RefSeq], active form of RhoA (GTP, is one of the subunits of myosin phosphatase, phosphorylated MBS and consequently inactivated myosin phosphatase, which is activated by GTP, which is also called the myosin-binding subunit of myosin phosphatase, which regulates the extent of phosphorylation of MLC, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells, Myosin phosphatase target subunit 1, RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms MBS M130
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMYPT1 (Ser507) Conjugated
Short name FITC Conjugated, MYPT1 (Ser507) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, MYPT1 (Ser507) (Antibody to)
Alternative techniqueantibodies
Identity 7618
Gene PPP1R12A
Long gene name protein phosphatase 1 regulatory subunit 12A
Synonyms gene MYPT1
Synonyms gene name protein phosphatase 1, regulatory (inhibitor) subunit 12A protein phosphatase 1, regulatory subunit 12A
Synonyms name myosin phosphatase-targeting subunit 1 myosin binding subunit
Locus 12q21, 2-q21, 31
Discovery year 1997-12-23
GenBank acession D87930
Entrez gene record 4659
Pubmed identfication 9286714
RefSeq identity NM_002480
Classification Ankyrin repeat domain containing Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000170100

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