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MYRIP/SLAC2-C Antibody

MYRIP/SLAC2-C Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMYRIP/SLAC2-C Primary Polyclonal Antibody
Also known asMYRIP/SLAC2-C PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMYRIP/SLAC2-C
SpecificityThis is a highly specific antibody against MYRIP/SLAC2-C
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MYRIP/SLAC2-C
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Additionally, Found in the basal microvilli of retinal pigment cells and in pre- and post-synaptic areas in photoreceptor cells , Once linked, Slac2-c contains one FYVE-type zinc finger and one Rab-binding domain and is able to bind actin-like proteins through its conserved C-terminal region, Slac2-c is involved in melanosome transport and functions to link Rab 27a with the actin-based motor proteins Myosin Va and Myosin VIIa, Slac2-c is thought to regulate the final steps of insulin exocytosis by mediating the interaction of secretory granules with the cortical actin cytoskeleton, heart, skin and liver, the Myosins are able to transport Rab 27a to retinal melanosomes, thereby linking the actin cytoskeleton with the melanosome membrane, Slac2-c is a Rab effector protein that is expressed in a variety of tissues including brain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Exophilin-8, Exophilin8, MYRIP_HUMAN, MyRIP, Myosin VIIA and Rab interacting protein, Myosin-VIIa- and Rab-interacting protein, SLAC 2C, SLAC2 C, SLAC2-C, SLAC2C, Slp homolog lacking C2 domains c, Slp homologue lacking C2 domains, Slp homologue lacking C2 domains c antibody Synaptotagmin like protein homologue lacking C2 domains c, exophilin, rab effector MYRIP, synaptotagmin-like protein homologue lacking C2 domains-c, exophilin 8
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMYRIP/SLAC2-C
Short nameMYRIP/SLAC2-C Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMYRIP/SLAC2-C (Antibody to)
Alternative techniqueantibodies
Identity 19156
Gene MYRIP
Long gene name myosin VIIA and Rab interacting protein
Synonyms DKFZp586F1018 exophilin-8 MyRIP SLAC2-C SLAC2C
Synonyms name synaptotagmin-like protein homologue lacking C2 domains-c rab effector MYRIP Slp homologue lacking C2 domains
Locus 3p22, 1
Discovery year 2002-09-13
GenBank acession AF396687
Entrez gene record 25924
Pubmed identfication 11964381 12221080
RefSeq identity NM_015460
Classification A-kinase anchoring proteins
Havana BLAST/BLAT OTTHUMG00000131392

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