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NALP12 Antibody

NALP12 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNALP12 Primary Polyclonal Antibody
Also known asNALP12 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNALP12
SpecificityThis is a highly specific antibody against NALP12
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NALP12
Gene ID number91662
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen IRAK-1, Like all other NALP family members, NALP12, NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes, TRAF6 and RIPK1 in activated monocytes, also known as Monarch-1, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain, has a C-terminal leucine-rich repeat (LRR) region, May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK, NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FCAS2, LRR and PYD containing protein 12, LRR and PYD domains-containing protein 12, Monarch 1, Monarch-1, NACHT, NACHT, NACHT, NAL12_HUMAN, NLR family, NLRP12, Nucleotide-binding oligomerization domain, PAN6, PYPAF7, PYRIN containing APAF1 like protein 7, PYRIN-containing APAF1-like protein 7, RNO, RNO2, Regulated by nitric oxide, leucine rich repeat and PYD containing 12, leucine rich repeat and pyrin domain containing 12, pyrin domain containing 12, 3, CLR19
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNALP12
Short nameNALP12 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNALP12 (Antibody to)
Alternative techniqueantibodies
Identity 22938
Gene NLRP12
Long gene name NLR family pyrin domain containing 12
Synonyms gene NALP12
Synonyms gene name NACHT, leucine rich repeat and PYD containing 12
Synonyms RNO2 PYPAF7 Monarch1 PAN6 CLR19, 3
Synonyms name leucine rich repeat and pyrin domain containing 12 , nucleotide-binding oligomerization domain
Locus 19q13, 42
Discovery year 2003-10-28
GenBank acession AY095146
Entrez gene record 91662
Pubmed identfication 12563287 12019269
RefSeq identity NM_144687
Classification NLR family Pyrin domain containing
Havana BLAST/BLAT OTTHUMG00000060776
Locus Specific Databases LRG_181

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