Name : NALP12 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4806574570
| Long name | ALEXA FLUOR 647 Conjugated, NALP12 Polyclonal Antibody |
| Also known as | Anti-NALP12 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NALP12 |
| Specificity | This is a highly specific antibody against NALP12 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NALP12 |
| Gene ID Number | 91662 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | IRAK-1, Like all other NALP family members, NALP12, NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes, TRAF6 and RIPK1 in activated monocytes, also known as Monarch-1, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain, has a C-terminal leucine-rich repeat (LRR) region, May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK, NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | RNO2 PYPAF7 Monarch1 PAN6 CLR19, 3 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the NALP12 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | NALP12 |
| Short name | NALP12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, NALP12 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 22938 |
| Gene | NLRP12 |
| Long gene name | NLR family pyrin domain containing 12 |
| Synonyms gene | NALP12 |
| Synonyms gene name | NACHT, leucine rich repeat and PYD containing 12 |
| Synonyms name | leucine rich repeat and pyrin domain containing 12 , nucleotide-binding oligomerization domain |
| Locus | 19q13, 42 |
| Discovery year | 2003-10-28 |
| GenBank acession | AY095146 |
| Entrez gene record | 91662 |
| Pubmed identfication | 12563287 12019269 |
| RefSeq identity | NM_144687 |
| Classification | NLR family Pyrin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000060776 |
| Locus Specific Databases | LRG_181 |