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NALP12 Antibody, FITC Conjugated

NALP12 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, NALP12 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNALP12
SpecificityThis is a highly specific antibody against NALP12
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human NALP12
Gene ID number91662
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background IRAK-1, Like all other NALP family members, NALP12, NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes, TRAF6 and RIPK1 in activated monocytes, also known as Monarch-1, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain, has a C-terminal leucine-rich repeat (LRR) region, May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK, NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms RNO2 PYPAF7 Monarch1 PAN6 CLR19, 3
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNALP12 Conjugated
Short name FITC Conjugated, NALP12 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, NALP12 (Antibody to)
Alternative techniqueantibodies
Identity 22938
Gene NLRP12
Long gene name NLR family pyrin domain containing 12
Synonyms gene NALP12
Synonyms gene name NACHT, leucine rich repeat and PYD containing 12
Synonyms name leucine rich repeat and pyrin domain containing 12 , nucleotide-binding oligomerization domain
Locus 19q13, 42
Discovery year 2003-10-28
GenBank acession AY095146
Entrez gene record 91662
Pubmed identfication 12563287 12019269
RefSeq identity NM_144687
Classification NLR family Pyrin domain containing
Havana BLAST/BLAT OTTHUMG00000060776
Locus Specific Databases LRG_181

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