Name : NALP4 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5196199088
| Long name | ALEXA FLUOR 647 Conjugated, NALP4 Polyclonal Antibody |
| Also known as | Anti-NALP4 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NALP4 |
| Specificity | This is a highly specific antibody against NALP4 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 370-420/994 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NALP4 |
| Gene ID Number | 147945 |
| Swiss Prot | Q96MN2 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, and its subsequent degradation, suggesting that it operates at a point of convergence in these two cytokine signaling pathways, May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | PYPAF4 FLJ32126 PAN2 RNH2 CLR19, 5 CT58 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the NALP4 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | NALP4 |
| Short name | NALP4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, NALP4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 22943 |
| Gene | NLRP4 |
| Long gene name | NLR family pyrin domain containing 4 |
| Synonyms gene | NALP4 |
| Synonyms gene name | NACHT, leucine rich repeat and PYD containing 4 |
| Synonyms name | leucine rich repeat and pyrin domain containing 4 cancer/testis antigen 58 , nucleotide-binding oligomerization domain |
| Locus | 19q13, 43 |
| Discovery year | 2003-10-28 |
| GenBank acession | AF479747 |
| Entrez gene record | 147945 |
| Pubmed identfication | 12563287 12019269 |
| RefSeq identity | NM_134444 |
| Classification | NLR family Pyrin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000181734 |