Name : NALP4 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8144889653
| Long name | Biotin Conjugated, NALP4 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NALP4 |
| Specificity | C and E Mouse variants, This antibody will detect multiple forms of NALP4, including the A, This is a highly specific antibody against NALP4 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 370-420/994 |
| Source | KLH conjugated synthetic peptide derived from human NALP4 |
| Gene ID number | 147945 |
| Swiss Prot | Q96MN2 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, and its subsequent degradation, suggesting that it operates at a point of convergence in these two cytokine signaling pathways, May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | PYPAF4 FLJ32126 PAN2 RNH2 CLR19, 5 CT58 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | NALP4 Conjugated |
| Short name | Conjugated, NALP4 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, NALP4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 22943 |
| Gene | NLRP4 |
| Long gene name | NLR family pyrin domain containing 4 |
| Synonyms gene | NALP4 |
| Synonyms gene name | NACHT, leucine rich repeat and PYD containing 4 |
| Synonyms name | leucine rich repeat and pyrin domain containing 4 cancer/testis antigen 58 , nucleotide-binding oligomerization domain |
| Locus | 19q13, 43 |
| Discovery year | 2003-10-28 |
| GenBank acession | AF479747 |
| Entrez gene record | 147945 |
| Pubmed identfication | 12563287 12019269 |
| RefSeq identity | NM_134444 |
| Classification | NLR family Pyrin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000181734 |