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NALP4 Antibody, FITC Conjugated

NALP4 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, NALP4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNALP4
Specificity C and E Mouse variants, This antibody will detect multiple forms of NALP4, including the A, This is a highly specific antibody against NALP4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range370-420/994
SourceKLH conjugated synthetic peptide derived from human NALP4
Gene ID number147945
Swiss ProtQ96MN2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, and its subsequent degradation, suggesting that it operates at a point of convergence in these two cytokine signaling pathways, May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms PYPAF4 FLJ32126 PAN2 RNH2 CLR19, 5 CT58
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNALP4 Conjugated
Short name FITC Conjugated, NALP4 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, NALP4 (Antibody to)
Alternative techniqueantibodies
Identity 22943
Gene NLRP4
Long gene name NLR family pyrin domain containing 4
Synonyms gene NALP4
Synonyms gene name NACHT, leucine rich repeat and PYD containing 4
Synonyms name leucine rich repeat and pyrin domain containing 4 cancer/testis antigen 58 , nucleotide-binding oligomerization domain
Locus 19q13, 43
Discovery year 2003-10-28
GenBank acession AF479747
Entrez gene record 147945
Pubmed identfication 12563287 12019269
RefSeq identity NM_134444
Classification NLR family Pyrin domain containing
Havana BLAST/BLAT OTTHUMG00000181734

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