| Long name | Nanog Primary Polyclonal Antibody |
| Also known as | Nanog PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Nanog |
| Specificity | This is a highly specific antibody against Nanog |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 90-140/305 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from mouse Nanog |
| Gene ID number | 71950 |
| Swiss Prot | Q80Z64 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, Acts as a transcriptional activator or repressor, Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3', Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes, Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, When overexpressed, leading to recruitment of the NuRD complex and subsequent repression of expression, promotes cells to enter into S phase and proliferation, Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 2412E2Rik, ES cell-associated protein 4, Early embryo specific expression NK-type homeobox protein, Homeobox protein NANOG, Homeobox transcription factor Nanog, Nanog, ecat4, ENK |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Nanog |
| Short name | Nanog Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Nanog (Antibody to) |
| Alternative technique | antibodies |
| Identity | 20857 |
| Gene | NANOG |
| Long gene name | Nanog homeobox |
| Synonyms | FLJ12581 FLJ40451 |
| Locus | 12p13, 31 |
| Discovery year | 2003-09-10 |
| GenBank acession | AB093576 |
| Entrez gene record | 79923 |
| Pubmed identfication | 12787505 12787504 |
| RefSeq identity | NM_024865 |
| Classification | NKL subclass homeoboxes and pseudogenes |
| Havana BLAST/BLAT | OTTHUMG00000166019 |
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