Name : Nanog Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2930023076
| Long name | ALEXA FLUOR 350 Conjugated, Nanog Polyclonal Antibody |
| Also known as | Anti-Nanog PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Nanog |
| Specificity | This is a highly specific antibody against Nanog |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 90-140/305 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from mouse Nanog |
| Gene ID Number | 71950 |
| Swiss Prot | Q80Z64 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, Acts as a transcriptional activator or repressor, Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3', Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes, Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, When overexpressed, leading to recruitment of the NuRD complex and subsequent repression of expression, promotes cells to enter into S phase and proliferation, Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | FLJ12581 FLJ40451 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | Nanog |
| Short name | Nanog Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, Nanog (Antibody to) |
| Alternative technique | antibodies |
| Identity | 20857 |
| Gene | NANOG |
| Long gene name | Nanog homeobox |
| Locus | 12p13, 31 |
| Discovery year | 2003-09-10 |
| GenBank acession | AB093576 |
| Entrez gene record | 79923 |
| Pubmed identfication | 12787505 12787504 |
| RefSeq identity | NM_024865 |
| Classification | NKL subclass homeoboxes and pseudogenes |
| Havana BLAST/BLAT | OTTHUMG00000166019 |