Name : NCKAP1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2349675426
| Long name | NCKAP1 Primary Polyclonal Antibody |
| Also known as | NCKAP1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | NCKAP1 |
| Specificity | This is a highly specific antibody against NCKAP1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human 12 NCKAP1 |
| Gene ID number | 10787 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Abi-1 and CYFIP1, NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, NAP125 is found at highest levels in heart, NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32, While widely expressed, also known as NCKAP1 (NCK-associated protein 1), brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, is a 1, p125Nap1 or membrane-associated protein HEM-2, suggesting a possible role in the disease, 1 and mouse chromosome 2 C3, 128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family, NAP125 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Membrane associated protein HEM2, Membrane-associated protein HEM-2, NAP 1, NAP1, NAP125, NCK associated protein, NCK associated protein 1, NCKP1_HUMAN, Nck-associated protein 1, Nckap1, p125Nap1, NCK associated protein 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | NCKAP1 |
| Short name | NCKAP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | NCK-associated protein 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | HEM2 and NAP1 and NAP125 and p125Nap1, NCKAP1 and IDBG-639791 and ENSBTAG00000033662 and 100300817, NCKAP1 and IDBG-76903 and ENSG00000061676 and 10787, Nckap1 and IDBG-183835 and ENSMUSG00000027002 and 50884, Plasma membranes, Rac GTPase binding, embryo and biological process this GO :0007417 and central nervous system development and biological process this GO :0007492 and endoderm development and biological process this GO :0008078 and mesodermal cell migration and biological process this GO :0010172 and embryonic body morphogenesis and biological process this GO :0010592 and positive regulation of lamellipodium assembly and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016601 and Rac protein signal transduction and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030032 and lamellipodium assembly and biological process this GO :0030903 and notochord development and biological process this GO :0030950 and establishment or maintenance of actin cytoskeleton polarity and biological process this GO :0031209 and SCAR complex and cellular component this GO :0031258 and lamellipodium membrane and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0032880 and regulation of protein localization and biological process this GO :0035050 and embryonic heart tube development and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042074 and cell migration involved in gastrulation and biological process this GO :0045087 and innate immune response and biological process this GO :0045175 and basal protein localization and biological process this GO :0045176 and apical protein localization and biological process this GO :0048339 and paraxial mesoderm development and biological process this GO :0048340 and paraxial mesoderm morphogenesis and biological process this GO :0048365 and Rac GTPase binding and molecular function this GO :0048570 and notochord morphogenesis and biological process this GO :0048617 and embryonic foregut morphogenesis and biological process this GO :0050821 and protein stabilization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :2000601 and positive regulation of Arp2/3 complex-mediated actin nucleation and biological process, this GO :0001701 and in utero embryonic development and biological process this GO :0001756 and somitogenesis and biological process this GO :0001843 and neural tube closure and biological process this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007354 and zy this GO tic determination of anterior/posterior axis, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0032403: protein complex binding and also this GO :0048365: Rac GTPase binding, this GO :0032403: protein complex binding, this GO :0048365: Rac GTPase binding, 101907541, NCK-associated protein 1 |
| Identity | 7666 |
| Gene | NCKAP1 |
| Long gene name | NCK associated protein 1 |
| Synonyms | Nap1 HEM2 NAP125 |
| Locus | 2q32, 1 |
| Discovery year | 1999-07-19 |
| GenBank acession | AB014509 |
| Entrez gene record | 10787 |
| Pubmed identfication | 10673335 12181570 9344857 |
| RefSeq identity | NM_205842 |
| Havana BLAST/BLAT | OTTHUMG00000132623 |