Name : NCKAP1 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6185684351
| Long name | FITC Conjugated, NCKAP1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NCKAP1 |
| Specificity | This is a highly specific antibody against NCKAP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human 12 NCKAP1 |
| Gene ID number | 10787 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Abi-1 and CYFIP1, NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, NAP125 is found at highest levels in heart, NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32, While widely expressed, also known as NCKAP1 (NCK-associated protein 1), brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, is a 1, p125Nap1 or membrane-associated protein HEM-2, suggesting a possible role in the disease, 1 and mouse chromosome 2 C3, 128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family, NAP125 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | Nap1 HEM2 NAP125 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | NCKAP1 Conjugated |
| Short name | FITC Conjugated, NCKAP1 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, NCK-associated protein 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | HEM2 and NAP1 and NAP125 and p125Nap1, NCKAP1 and IDBG-639791 and ENSBTAG00000033662 and 100300817, NCKAP1 and IDBG-76903 and ENSG00000061676 and 10787, Nckap1 and IDBG-183835 and ENSMUSG00000027002 and 50884, Plasma membranes, Rac GTPase binding, embryo and biological process this GO :0007417 and central nervous system development and biological process this GO :0007492 and endoderm development and biological process this GO :0008078 and mesodermal cell migration and biological process this GO :0010172 and embryonic body morphogenesis and biological process this GO :0010592 and positive regulation of lamellipodium assembly and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016601 and Rac protein signal transduction and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030032 and lamellipodium assembly and biological process this GO :0030903 and notochord development and biological process this GO :0030950 and establishment or maintenance of actin cytoskeleton polarity and biological process this GO :0031209 and SCAR complex and cellular component this GO :0031258 and lamellipodium membrane and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0032880 and regulation of protein localization and biological process this GO :0035050 and embryonic heart tube development and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042074 and cell migration involved in gastrulation and biological process this GO :0045087 and innate immune response and biological process this GO :0045175 and basal protein localization and biological process this GO :0045176 and apical protein localization and biological process this GO :0048339 and paraxial mesoderm development and biological process this GO :0048340 and paraxial mesoderm morphogenesis and biological process this GO :0048365 and Rac GTPase binding and molecular function this GO :0048570 and notochord morphogenesis and biological process this GO :0048617 and embryonic foregut morphogenesis and biological process this GO :0050821 and protein stabilization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :2000601 and positive regulation of Arp2/3 complex-mediated actin nucleation and biological process, this GO :0001701 and in utero embryonic development and biological process this GO :0001756 and somitogenesis and biological process this GO :0001843 and neural tube closure and biological process this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007354 and zy this GO tic determination of anterior/posterior axis, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0032403: protein complex binding and also this GO :0048365: Rac GTPase binding, this GO :0032403: protein complex binding, this GO :0048365: Rac GTPase binding, 101907541, NCK-associated protein 1 |
| Identity | 7666 |
| Gene | NCKAP1 |
| Long gene name | NCK associated protein 1 |
| Locus | 2q32, 1 |
| Discovery year | 1999-07-19 |
| GenBank acession | AB014509 |
| Entrez gene record | 10787 |
| Pubmed identfication | 10673335 12181570 9344857 |
| RefSeq identity | NM_205842 |
| Havana BLAST/BLAT | OTTHUMG00000132623 |