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NDEL1(Ser242) Antibody, Biotin Conjugated

NDEL1(Ser242) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, NDEL1(Ser242) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNDEL1 Ser242
SpecificityThis is a highly specific antibody against NDEL1 Ser242
ModificationPhosphorylation
Modification siteSer242
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range230-260/345
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human NDEL1 around the phosphorylation site of Ser242
Gene ID number81565
Swiss ProtQ9GZM8
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also positively regulates the activity of the minus-end directed microtubule motor protein dynein, Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate, Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL, May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends, May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome, Plays a role, Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, in the regulation of neurite outgrowth, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome, together with DISC1, which instead requires NDE1, Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms NUDEL MITAP1 NDE1L1 NDE2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNDEL1(Ser242) Conjugated
Short name Conjugated, NDEL1(Ser242) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, NDEL1(Ser242) (Antibody to)
Alternative techniqueantibodies
Identity 17620
Gene NDEL1
Long gene name nudE neurodevelopment protein 1 like 1
Synonyms gene name nidulans)-like 1 , nidulans)-like 1 nudE nuclear distribution E homolog (A, nudE nuclear distribution gene E homolog (A
Locus 17p13, 1
Discovery year 2003-04-10
GenBank acession AF182078
Entrez gene record 81565
Pubmed identfication 11163260 11163259
RefSeq identity NM_030808
Havana BLAST/BLAT OTTHUMG00000108193

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