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NDUFS7 Antibody

NDUFS7 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNDUFS7 Primary Polyclonal Antibody
Also known asNDUFS7 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNDUFS7
SpecificityThis is a highly specific antibody against NDUFS7
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NDUFS7
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen As a subunit of mitochondrial complex I, By oxidizing NADH that is produced in the Krebs cycle, Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions, also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, Located in the mitochondrial inner membrane
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 20kDa NADHcoenzyme Q reductase, 20kDa NADHcoenzyme Q reductase, CI-20kD, Complex I 20kDa subunit, Complex I mitochondrial respiratory chain 20 KD subunit, Complex I-20kD, MGC120002, MY017, NADH coenzyme Q reductase, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, NADH dehydrogenase ubiquinone Fe S protein 7 20kDa NADH coenzyme Q reductase, NADH dehydrogenase ubiquinone FeS protein 7, NADH dehydrogenase ubiquinone FeS protein7, NADH-ubiquinone oxidoreductase 20 kDa subunit, NADH:ubiquinone oxidoreductase PSST subunit, NADHcoenzyme Q reductase, NDUS7_HUMAN, Ndufs7, PSST, PSST subunit, mitochondrial, CI 20
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNDUFS7
Short nameNDUFS7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNDUFS7 (Antibody to)
Alternative techniqueantibodies
Identity 7714
Gene NDUFS7
Long gene name NADH:ubiquinone oxidoreductase core subunit S7
Synonyms gene name 20kDa (NADH-coenzyme Q reductase) , NADH dehydrogenase (ubiquinone) Fe-S protein 7 (20kD) (NADH-coenzyme Q reductase) NADH dehydrogenase (ubiquinone) Fe-S protein 7
Synonyms PSST FLJ46880 FLJ45860 CI-20
Synonyms name complex I 20kDa subunit NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
Locus 19p13, 3
Discovery year 1996-07-26
GenBank acession AF115969
Entrez gene record 374291
Pubmed identfication 8938450
RefSeq identity NM_024407
Classification NADH:ubiquinone oxidoreductase core subunits
Havana BLAST/BLAT OTTHUMG00000168077

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