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NDUFS7 Antibody, FITC Conjugated

NDUFS7 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, NDUFS7 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNDUFS7
SpecificityThis is a highly specific antibody against NDUFS7
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human NDUFS7
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background As a subunit of mitochondrial complex I, By oxidizing NADH that is produced in the Krebs cycle, Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions, also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, Located in the mitochondrial inner membrane
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms PSST FLJ46880 FLJ45860 CI-20
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNDUFS7 Conjugated
Short name FITC Conjugated, NDUFS7 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, NDUFS7 (Antibody to)
Alternative techniqueantibodies
Identity 7714
Gene NDUFS7
Long gene name NADH:ubiquinone oxidoreductase core subunit S7
Synonyms gene name 20kDa (NADH-coenzyme Q reductase) , NADH dehydrogenase (ubiquinone) Fe-S protein 7 (20kD) (NADH-coenzyme Q reductase) NADH dehydrogenase (ubiquinone) Fe-S protein 7
Synonyms name complex I 20kDa subunit NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
Locus 19p13, 3
Discovery year 1996-07-26
GenBank acession AF115969
Entrez gene record 374291
Pubmed identfication 8938450
RefSeq identity NM_024407
Classification NADH:ubiquinone oxidoreductase core subunits
Havana BLAST/BLAT OTTHUMG00000168077

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