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NEDD4 Antibody, ALEXA FLUOR 555

NEDD4 Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, NEDD4 Polyclonal Antibody
Also known asAnti-NEDD4 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNEDD4
SpecificityThis is a highly specific antibody against NEDD4
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range861-890/1319
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NEDD4
Gene ID Number4734
Swiss ProtP46934
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen According to PubMed:18562292 the direct link between NEDD4 and PTEN regulation through polyubiquitination described in PubMed:17218260 is questionable, Involved in the budding of many viruses, Involved in the pathway leading to the degradation of VEGFR-2/KDFR, Involved in the ubiquitination of ebola virus VP40 protein and this ubiquitination plays a role in facilitating viral budding, Involved in ubiquitination of ERBB4 intracellular domain E4ICD, Monoubiquitinates IGF1R at multiple sites, Part of a signaling complex composed of NEDD4, Promotes ubiquitination of RAPGEF2, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development, Ubiquitinates FGFR1, Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2, independently of its ubiquitin-ligase activity, leading to receptor internalization and degradation in lysosomes, thus leading to receptor internalization and degradation in lysosomes, E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms KIAA0093 MGC176705 NEDD4-1 RPF1
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetNEDD4
Short nameNEDD4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, NEDD4 (Antibody to)
Alternative techniqueantibodies
Identity 7727
Gene NEDD4
Long gene name E3 ubiquitin protein ligase , developmentally down-regulated 4, neural precursor cell expressed
Synonyms gene name developmentally down-regulated 4 , neural precursor cell expressed
Synonyms name receptor-potentiating factor 1
Locus 15q21, 3
Discovery year 1994-01-21
GenBank acession D42055
Entrez gene record 4734
Pubmed identfication 9073511 8649367
RefSeq identity NM_198400
Havana BLAST/BLAT OTTHUMG00000132015

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