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NEDD4 Antibody, Cy3 Conjugated

NEDD4 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, NEDD4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNEDD4
SpecificityThis is a highly specific antibody against NEDD4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range861-890/1319
SourceKLH conjugated synthetic peptide derived from human NEDD4
Gene ID number4734
Swiss ProtP46934
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background According to PubMed:18562292 the direct link between NEDD4 and PTEN regulation through polyubiquitination described in PubMed:17218260 is questionable, Involved in the budding of many viruses, Involved in the pathway leading to the degradation of VEGFR-2/KDFR, Involved in the ubiquitination of ebola virus VP40 protein and this ubiquitination plays a role in facilitating viral budding, Involved in ubiquitination of ERBB4 intracellular domain E4ICD, Monoubiquitinates IGF1R at multiple sites, Part of a signaling complex composed of NEDD4, Promotes ubiquitination of RAPGEF2, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development, Ubiquitinates FGFR1, Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2, independently of its ubiquitin-ligase activity, leading to receptor internalization and degradation in lysosomes, thus leading to receptor internalization and degradation in lysosomes, E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms KIAA0093 MGC176705 NEDD4-1 RPF1
Properties 1 of the NEDD4 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNEDD4 Conjugated
Short name Conjugated, NEDD4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, NEDD4 (Antibody to)
Alternative techniqueantibodies
Identity 7727
Gene NEDD4
Long gene name E3 ubiquitin protein ligase , developmentally down-regulated 4, neural precursor cell expressed
Synonyms gene name developmentally down-regulated 4 , neural precursor cell expressed
Synonyms name receptor-potentiating factor 1
Locus 15q21, 3
Discovery year 1994-01-21
GenBank acession D42055
Entrez gene record 4734
Pubmed identfication 9073511 8649367
RefSeq identity NM_198400
Havana BLAST/BLAT OTTHUMG00000132015

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