| Long name | ALEXA FLUOR 488 Conjugated, NEDD4L (Ser342) Polyclonal Antibody |
| Also known as | Anti-NEDD4L Ser342 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NEDD4L Ser342 |
| Specificity | This is a highly specific antibody against NEDD4L Ser342 |
| Modification | Phosphorylation |
| Modification Site | Ser342 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human NEDD4L around the phosphorylation site of Ser342 |
| Gene ID Number | 23327 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | EAAT1 or CLC5, Furthermore, Kv1, Nav1, Nav1, Nav1, Nav1, Nav1, This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation, and promotes the ubiquitination and degradation of SGK, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, 2, 3, 3, 5, 7, 8, E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | KIAA0439 RSP5 NEDD4-2 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the NEDD4L (Ser342) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | NEDD4L (Ser342) |
| Short name | NEDD4L (Ser342) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, E3 ubiquitin protein ligase (Ser342) (Antibody to), developmentally down-regulated 4-like, neural precursor cellular expressed |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006513 and protein monoubiquitination and biological process this GO :0006814 and sodium ion transport and biological process this GO :0006883 and cellular sodium ion homeostasis and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007588 and excretion and biological process this GO :0009651 and response to salt stress and biological process this GO :0010038 and response to metal ion and biological process this GO :0010467 and gene expression and biological process this GO :0010765 and positive regulation of sodium ion transport and biological process this GO :0010766 and negative regulation of sodium ion transport and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016032 and viral process and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0017080 and sodium channel regulator activity and molecular function this GO :0019058 and viral life cycle and biological process this GO :0019870 and potassium channel inhibitor activity and molecular function this GO :0019871 and sodium channel inhibitor activity and molecular function this GO :0030104 and water homeostasis and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0034765 and regulation of ion transmembrane transport and biological process this GO :0042176 and regulation of protein catabolic process and biological process this GO :0042391 and regulation of membrane potential and biological process this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0043162 and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway and biological process this GO :0044325 and ion channel binding and molecular function this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045807 and positive regulation of endocytosis and biological process this GO :0055085 and transmembrane transport and biological process this GO :0060306 and regulation of membrane repolarization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070936 and protein K48-linked ubiquitination and biological process this GO :0086005 and ventricular cardiac muscle cell action potential and biological process this GO :1901016 and regulation of potassium ion transmembrane transporter activity and biological process this GO :1901017 and negative regulation of potassium ion transmembrane transporter activity and biological process this GO :1901380 and negative regulation of potassium ion transmembrane transport and biological process this GO :1902306 and negative regulation of sodium ion transmembrane transport and biological process this GO :2000009 and negative regulation of protein localization to cell surface and biological process this GO :2000650 and negative regulation of sodium ion transmembrane transporter activity and biological process this GO :2000810 and regulation of tight junction assembly and biological process this GO :2001259 and positive regulation of cation channel activity and biological process this GO :2001288 and positive regulation of caveolin-mediated endocytosis and biological process, E3 ubiquitin protein ligase, NEDD4L and IDBG-3835 and ENSG00000049759 and 23327, NEDD4L and IDBG-644828 and ENSBTAG00000005412 and 510003, Nedd4l and IDBG-154290 and ENSMUSG00000024589 and 83814, developmentally down-regulated 4-like, hNEDD4-2 and NEDD4-2 and NEDD4, ion channel binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0003085 and negative regulation of systemic arterial blood pressure and biological process this GO :0003254 and regulation of membrane depolarization and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0015459: potassium channel regulator activity and also this GO :0016874: ligase activity and also this GO :0017080: sodium channel regulator activity and also this GO :0019870: potassium channel inhibitor activity and also this GO :0019871: sodium channel inhibitor activity and also this GO :0044325: ion channel binding, this GO :0005515: protein binding, this GO :0015459: potassium channel regulator activity, this GO :0016874: ligase activity, this GO :0017080: sodium channel regulator activity, this GO :0019870: potassium channel inhibitor activity, this GO :0019871: sodium channel inhibitor activity, this GO :0044325: ion channel binding, 2 and RSP5, neural precursor cell expressed |
| Identity | 7728 |
| Gene | NEDD4L |
| Long gene name | E3 ubiquitin protein ligase , developmentally down-regulated 4-like, neural precursor cell expressed |
| Synonyms gene name | developmentally down-regulated 4-like , neural precursor cell expressed |
| Locus | 18q21, 31 |
| Discovery year | 2000-03-14 |
| GenBank acession | AF210730 |
| Entrez gene record | 23327 |
| Pubmed identfication | 10594025 11244092 18322022 |
| Classification | C2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000179875 |
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