Name : NEDD8 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9964486384
| Long name | ALEXA FLUOR 594 Conjugated, NEDD8 Polyclonal Antibody |
| Also known as | Anti-NEDD8 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NEDD8 |
| Specificity | This is a highly specific antibody against NEDD8 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NEDD8 |
| Gene ID Number | 4738 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Apg12 and Hub1, Cullins are subunits of an E3 ubiquitin ligase complex called the Skp1 /Cul1/Cdc53 F box (SCF), Examples of UBLs are SUMO, In contrast to UBLs, NEDD8 shows 80% homology to ubiquitin, Proteins of the second class include Parkin, RAD23 and DSK2, Rub1 (also called Nedd8), Rub1 and the corresponding human homolog NEDD8 are activated by the E1 ubiquitin activating enzyme UBA2, Rub1 modification may regulate SCF function or localization, The SCF promotes transfer of ubiquitin from a ubiquitin conjugating enzyme (E2) to the target protein, The best known targets of Rub1 modification are members of the cullin family, These proteins contain domains that are related to ubiquitin but are otherwise unrelated to each other, UDPs are not proteolytically processed or conjugated to other proteins, are designated ubiquitin domain proteins (UDPs), that forms isopeptide linkages between thio esters, ubiquitin-like modifiers (UBLs) function as modifiers in a manner analogous to that of ubiquitin, Ubiquitin like proteins fall into two classes: the first class |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | Nedd-8 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | NEDD8 |
| Short name | NEDD8 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, NEDD8 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7732 |
| Gene | NEDD8 |
| Long gene name | developmentally down-regulated 8 , neural precursor cell expressed |
| Locus | 14q12 |
| Discovery year | 1994-01-21 |
| GenBank acession | D23662 |
| Entrez gene record | 4738 |
| Pubmed identfication | 9353319 |
| RefSeq identity | NM_006156 |
| Havana BLAST/BLAT | OTTHUMG00000029325 |