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NEK2 Antibody

NEK2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNEK2 Primary Polyclonal Antibody
Also known asNEK2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNEK2
SpecificityThis is a highly specific antibody against NEK2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range5-55/445
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NEK2
Gene ID number4751
Swiss ProtP51955
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CEP25 and NINL, Essential for localization of MAD2L1 to kinetochore and MAPK1 and NPM1 to the centrosome, Involved in regulation of mitotic checkpoint protein complex via phosphorylation of CDC2 and MAD2L1, Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells, Isoform 2, NECAB3 and NPM1, Phosphorylates: PPP1CC, Plays an active role in chromatin condensation during the first meiotic division through phosphorylation of HMGA2, Regulates centrosome separation (essential for the formation of bipolar spindles and high-fidelity chromosome separation) by phosphorylating centrosomal proteins such as CROCC, Regulates kinetochore microtubule attachment stability in mitosis via phosphorylation of NDC8, SGOL1, does not, resulting in their displacement from the centrosomes, which is not present in the nucleolus, Protein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names HSPK 21, HsPK21, NEK2, NEK2A, Never in mitosis A-related kinase 2, NimA-like protein kinase 1, NimA-related protein kinase 2, PPP1R111, RP67, Serine/threonine-protein kinase Nek2, NLK1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNEK2
Short nameNEK2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNEK2 (Antibody to)
Alternative techniqueantibodies
Identity 7745
Gene NEK2
Long gene name NIMA related kinase 2
Synonyms gene name NIMA (never in mitosis gene a)-related kinase 2
Synonyms NLK1 NEK2A RP67 PPP1R111
Synonyms name HsPK 21 protein phosphatase 1, regulatory subunit 111
Locus 1q32, 3
Discovery year 1998-08-26
GenBank acession U11050
Entrez gene record 4751
Pubmed identfication 8274451 24043777
RefSeq identity NM_002497
Classification Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000037121

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