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NEK2 Antibody, Cy7 Conjugated

NEK2 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, NEK2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNEK2
SpecificityThis is a highly specific antibody against NEK2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range5-55/445
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human NEK2
Gene ID number4751
Swiss ProtP51955
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CEP25 and NINL, Essential for localization of MAD2L1 to kinetochore and MAPK1 and NPM1 to the centrosome, Involved in regulation of mitotic checkpoint protein complex via phosphorylation of CDC2 and MAD2L1, Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells, Isoform 2, NECAB3 and NPM1, Phosphorylates: PPP1CC, Plays an active role in chromatin condensation during the first meiotic division through phosphorylation of HMGA2, Regulates centrosome separation (essential for the formation of bipolar spindles and high-fidelity chromosome separation) by phosphorylating centrosomal proteins such as CROCC, Regulates kinetochore microtubule attachment stability in mitosis via phosphorylation of NDC8, SGOL1, does not, resulting in their displacement from the centrosomes, which is not present in the nucleolus, Protein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms NLK1 NEK2A RP67 PPP1R111
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetNEK2 Conjugated
Short name Conjugated, NEK2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, NEK2 (Antibody to)
Alternative techniqueantibodies
Identity 7745
Gene NEK2
Long gene name NIMA related kinase 2
Synonyms gene name NIMA (never in mitosis gene a)-related kinase 2
Synonyms name HsPK 21 protein phosphatase 1, regulatory subunit 111
Locus 1q32, 3
Discovery year 1998-08-26
GenBank acession U11050
Entrez gene record 4751
Pubmed identfication 8274451 24043777
RefSeq identity NM_002497
Classification Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000037121

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