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NEMO Antibody, ALEXA FLUOR 350

NEMO Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, NEMO Polyclonal Antibody
Also known asAnti-NEMO PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNEMO
SpecificityThis is a highly specific antibody against NEMO
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range370-419/419
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NEMO
Gene ID Number8517
Swiss ProtQ9Y6K9
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Also considered to be a mediator for TAX activation of NF-kappa-B, Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity, Essential for viral activation of IRF3, However, Involved in TLR3- and IFIH1-mediated antiviral innate response, Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly, this function requires 'Lys-27'-linked polyubiquitination, Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms IKK-gamma NEMO Fip3p FIP-3 FIP3 ZC2HC9
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetNEMO
Short nameNEMO Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, NEMO (Antibody to)
Alternative techniqueantibodies
Identity 5961
Gene IKBKG
Long gene name inhibitor of nuclear factor kappa B kinase subunit gamma
Synonyms gene IP2 IP1
Synonyms gene name incontinentia pigmenti inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Locus Xq28
Discovery year 1998-09-30
GenBank acession AF074382
Entrez gene record 8517
Pubmed identfication 9751060 10087442 11590134
RefSeq identity NM_003639
Classification Zinc fingers C2HC-type
Havana BLAST/BLAT OTTHUMG00000024234
Locus Specific Databases IKBKGbase: Mutation registry for Nemo deficiency Mental Retardation database LRG_70

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