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NEMO Antibody, Biotin Conjugated

NEMO Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, NEMO Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNEMO
SpecificityThis is a highly specific antibody against NEMO
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range370-419/419
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human NEMO
Gene ID number8517
Swiss ProtQ9Y6K9
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also considered to be a mediator for TAX activation of NF-kappa-B, Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity, Essential for viral activation of IRF3, However, Involved in TLR3- and IFIH1-mediated antiviral innate response, Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly, this function requires 'Lys-27'-linked polyubiquitination, Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms IKK-gamma NEMO Fip3p FIP-3 FIP3 ZC2HC9
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNEMO Conjugated
Short name Conjugated, NEMO Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, NEMO (Antibody to)
Alternative techniqueantibodies
Identity 5961
Gene IKBKG
Long gene name inhibitor of nuclear factor kappa B kinase subunit gamma
Synonyms gene IP2 IP1
Synonyms gene name incontinentia pigmenti inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Locus Xq28
Discovery year 1998-09-30
GenBank acession AF074382
Entrez gene record 8517
Pubmed identfication 9751060 10087442 11590134
RefSeq identity NM_003639
Classification Zinc fingers C2HC-type
Havana BLAST/BLAT OTTHUMG00000024234
Locus Specific Databases IKBKGbase: Mutation registry for Nemo deficiency Mental Retardation database LRG_70

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