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NEMO Antibody, Cy5.5 Conjugated

NEMO Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, NEMO Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNEMO
SpecificityThis is a highly specific antibody against NEMO
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range370-419/419
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human NEMO
Gene ID number8517
Swiss ProtQ9Y6K9
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also considered to be a mediator for TAX activation of NF-kappa-B, Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity, Essential for viral activation of IRF3, However, Involved in TLR3- and IFIH1-mediated antiviral innate response, Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly, this function requires 'Lys-27'-linked polyubiquitination, Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms IKK-gamma NEMO Fip3p FIP-3 FIP3 ZC2HC9
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetNEMO Conjugated
Short name Conjugated, NEMO Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, NEMO (Antibody to)
Alternative techniqueantibodies
Identity 5961
Gene IKBKG
Long gene name inhibitor of nuclear factor kappa B kinase subunit gamma
Synonyms gene IP2 IP1
Synonyms gene name incontinentia pigmenti inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Locus Xq28
Discovery year 1998-09-30
GenBank acession AF074382
Entrez gene record 8517
Pubmed identfication 9751060 10087442 11590134
RefSeq identity NM_003639
Classification Zinc fingers C2HC-type
Havana BLAST/BLAT OTTHUMG00000024234
Locus Specific Databases IKBKGbase: Mutation registry for Nemo deficiency Mental Retardation database LRG_70

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