| Alternative name 1 | 75kD, Clone: NGFR 5, Mab anti-Human, Nerve Growth Factor Receptor (NGFR) |
| Alternative name 2 | 75kD, Clone: NGFR 5, Mab antibody-Human, Nerve Growth Factor Receptor (NGFR) |
| Alternative name 3 | 75kD, Clone: NGFR 5, Mab antibody-Homo sapiens, Nerve Growth Factor Receptor (NGFR) |
| Alternative name 4 | anti-Nerve Growth Factor Receptor NGFR 75kD Clone: NGFR 5 |
| Alternative name 5 | Nerve Growth Factor Receptor NGFR 75kD Clone: NGFR 5 |
| Clonality | Monoclonal Antibody |
| Description | Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling | Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory | For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| French translation | anticorps |
| Gene target | Monoclonal, NGFR 5, Nerve Growth Factor Receptor (NGFR) 75kD |
| Short name | Clone: NGFR 5, Mouse Monoclonal antibody-, Nerve Growth Factor Receptor (NGFR) 75kD |
| Technique | Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species | Humans, Mouses, Human |
| Alternative name | 75kD, Mouse monoclonal (Antibody to)-H, clonality: nerve growth factor receptor 5, sapiens, Nerve Growth Factor Receptor (nerve growth factor receptor) |
| Alternative technique | murine |
| Alternative to gene target | CD271 and Gp80-LNGFR and p75(NTR) and p75NTR and TNFRSF16, NGFR and IDBG-57653 and ENSG00000064300 and 4804, NGFR and IDBG-638806 and ENSBTAG00000020979 and 353110, Ngfr and IDBG-209608 and ENSMUSG00000000120 and 18053, nerve growth factor binding, nuclei, this GO :0004871 and signal transducer activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005035 and death receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006886 and intracellular protein transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0007417 and central nervous system development and biological process this GO :0009986 and cell surface and cellular component this GO :0010468 and regulation of gene expression and biological process this GO :0012501 and programmed cell death and biological process this GO :0016048 and detection of temperature stimulus and biological process this GO :0017137 and Rab GTPase binding and molecular function this GO :0021675 and nerve development and biological process this GO :0031069 and hair follicle morphogenesis and biological process this GO :0031293 and membrane protein intracellular domain proteolysis and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032922 and circadian regulation of gene expression and biological process this GO :0040037 and negative regulation of fibroblast growth factor receptor signaling pathway and biological process this GO :0042488 and positive regulation of odontogenesis of dentin-containing tooth and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043588 and skin development and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048406 and nerve growth factor binding and molecular function this GO :0050770 and regulation of axonogenesis and biological process this GO :0050771 and negative regulation of axonogenesis and biological process this GO :0050772 and positive regulation of axonogenesis and biological process this GO :0051799 and negative regulation of hair follicle development and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097481 and neuronal postsynaptic density and cellular component this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process this GO :2001273 and regulation of glucose import in response to insulin stimulus and biological process, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0004872: receptor activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005035: death receptor activity and also this GO :0005515: protein binding and also this GO :0017137: Rab GTPase binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0048406: nerve growth factor binding, this GO :0004872: receptor activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005035: death receptor activity, this GO :0005515: protein binding, this GO :0017137: Rab GTPase binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0048406: nerve growth factor binding, nerve growth factor receptor |
| Identity | 7809 |
| Gene | NGFR |
| Long gene name | nerve growth factor receptor |
| Synonyms gene name | member 16) , nerve growth factor receptor (TNFR superfamily |
| Synonyms | TNFRSF16 CD271 p75NTR |
| Synonyms name | low affinity nerve growth factor receptor TNFR superfamily, member 16 |
| Locus | 17q21, 33 |
| Discovery year | 2001-06-22 |
| GenBank acession | M14764 |
| Entrez gene record | 4804 |
| Pubmed identfication | 3022937 3006050 |
| Classification | CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT | OTTHUMG00000161495 |
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