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Neurexin 2 Antibody

Neurexin 2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNeurexin 2 Primary Polyclonal Antibody
Also known asNeurexin 2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNeurexin 2
SpecificityThis is a highly specific antibody against Neurexin 2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Neurexin 2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Caspr (for Contactin-Associated Protein 1, Caspr and the closely related Caspr2, Caspr exists at the paranodal junctions, Caspr may play a role in the communication of glial cells and neurons during development, Neurexins, Neurexins I-III are expressed as a and b isoforms, Sex hormone-binding)-domains separated by EGF domains, Specifically, The a isoforms are made of three cassettes, The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin, The b isoforms have only one LNS-domain, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), also designated Paranodin in mouse), and binds to the surface glycoprotein Contactin, and play a role in the formation and remodeling of synapes, bind to neuroligins, contains an extracellular domain similar to the other three neurexins, demarcate distinct subdomains in myelinated axons, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal, neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV), which contain two LNS (Laminin A, which include neurexin I (NRXN1), while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region, Neurexins comprise a family of neuronal cell surface proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NRX2A_HUMAN, NRXN 2, NRXN-2, NRXN2, Neurexin II, Neurexin II alpha, Neurexin-2, Neurexin2, Neurexin 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNeurexin 2
Short nameNeurexin 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNeurexin 2 (Antibody to)
Alternative techniqueantibodies
Identity 8009
Gene NRXN2
Long gene name neurexin 2
Synonyms name neurexin II
Locus 11q13, 1
Discovery year 1998-10-14
Entrez gene record 9379
Pubmed identfication 1621094
RefSeq identity NM_015080
Havana BLAST/BLAT OTTHUMG00000045214

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