Name : Neurexin 2 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4664234104
| Long name | ALEXA FLUOR 488 Conjugated, Neurexin 2 Polyclonal Antibody |
| Also known as | Anti-Neurexin 2 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Neurexin 2 |
| Specificity | This is a highly specific antibody against Neurexin 2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Neurexin 2 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Caspr (for Contactin-Associated Protein 1, Caspr and the closely related Caspr2, Caspr exists at the paranodal junctions, Caspr may play a role in the communication of glial cells and neurons during development, Neurexins, Neurexins I-III are expressed as a and b isoforms, Sex hormone-binding)-domains separated by EGF domains, Specifically, The a isoforms are made of three cassettes, The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin, The b isoforms have only one LNS-domain, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), also designated Paranodin in mouse), and binds to the surface glycoprotein Contactin, and play a role in the formation and remodeling of synapes, bind to neuroligins, contains an extracellular domain similar to the other three neurexins, demarcate distinct subdomains in myelinated axons, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal, neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV), which contain two LNS (Laminin A, which include neurexin I (NRXN1), while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region, Neurexins comprise a family of neuronal cell surface proteins |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Neurexin 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Neurexin 2 |
| Short name | Neurexin 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Neurexin 2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8009 |
| Gene | NRXN2 |
| Long gene name | neurexin 2 |
| Synonyms name | neurexin II |
| Locus | 11q13, 1 |
| Discovery year | 1998-10-14 |
| Entrez gene record | 9379 |
| Pubmed identfication | 1621094 |
| RefSeq identity | NM_015080 |
| Havana BLAST/BLAT | OTTHUMG00000045214 |