| Alternative name 1 | Clone: 3H8, Mab anti-, NEUROD1 |
| Alternative name 2 | Clone: 3H8, Mab antibody-, NEUROD1 |
| Alternative name 3 | Clone: 3H8, Mab antibody-, NEUROD1 |
| Alternative name 4 | anti-NEUROD1 Clone: 3H8 |
| Alternative name 5 | NEUROD1 Clone: 3H8 |
| Clonality | Monoclonal Antibody |
| Description | Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling | Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory | For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| French translation | anticorps |
| Gene target | Monoclonal 3H8, NEUROD1 |
| Short name | Mouse Monoclonal antibody- Clone: 3H8, NEUROD1 |
| Technique | Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species | Mouses, Mouse |
| Alternative name | Mouse monoclonal (Antibody to)-, clonality: 3H8, neuronal differentiation 1 |
| Alternative technique | murine |
| Alternative to gene target | BETA2 and BHF-1 and bHLHa3 and MODY6 and NEUROD, BT, DNA-templated and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0007263 and nitric oxide mediated signal transduction and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0009749 and response to glucose and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0021542 and dentate gyrus development and biological process this GO :0021549 and cerebellum development and biological process this GO :0022008 and neurogenesis and biological process this GO :0023019 and signal transduction involved in regulation of gene expression and biological process this GO :0030073 and insulin secretion and biological process this GO :0030902 and hindbrain development and biological process this GO :0031018 and endocrine pancreas development and biological process this GO :0035881 and amacrine cell differentiation and biological process this GO :0035883 and enteroendocrine cell differentiation and biological process this GO :0042493 and response to drug and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045165 and cell fate commitment and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045664 and regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046426 and negative regulation of JAK-STAT cascade and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048562 and embryonic organ morphogenesis and biological process this GO :0048839 and inner ear development and biological process this GO :0050796 and regulation of insulin secretion and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0060730 and regulation of intestinal epithelial structure maintenance and biological process this GO :0070888 and E-box binding and molecular function this GO :0071156 and regulation of cell cycle arrest and biological process this GO :0071333 and cellular response to glucose stimulus and biological process this GO :2000675 and negative regulation of type B pancreatic cell apoptotic process and biological process this GO :2000679 and positive regulation of transcription regulatory region DNA binding and biological process, E-box binding, NEUROD1 and IDBG-76792 and ENSG00000162992 and 4760, Neurod1 and IDBG-183353 and ENSMUSG00000034701 and 18012, nuclei, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001102 and RNA polymerase II activating transcription factor binding and molecular function this GO :0001105 and RNA polymerase II transcription coactivator activity and molecular function this GO :0003326 and pancreatic A cell fate commitment and biological process this GO :0003329 and pancreatic PP cell fate commitment and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001102: RNA polymerase II activating transcription factor binding and also this GO :0001105: RNA polymerase II transcription coactivator activity and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0046982: protein heterodimerization activity and also this GO :0046983: protein dimerization activity and also this GO :0070888: E-box binding, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001102: RNA polymerase II activating transcription factor binding, this GO :0001105: RNA polymerase II transcription coactivator activity, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003690: double-stranded DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003713: transcription coactivator activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0043565: sequence-specific DNA binding, this GO :0046982: protein heterodimerization activity, this GO :0046983: protein dimerization activity, this GO :0070888: E-box binding, 104022 and IDBG-648841 and ENSBTAG00000001755 and 539487, neuronal differentiation 1 |
| Identity | 7762 |
| Gene | NEUROD1 |
| Long gene name | neuronal differentiation 1 |
| Synonyms gene | NEUROD |
| Synonyms gene name | neurogenic differentiation 1 |
| Synonyms | BETA2 BHF-1 NeuroD bHLHa3 MODY6 |
| Synonyms name | beta-cell E-box transactivator 2 neurogenic helix-loop-helix protein NEUROD |
| Locus | 2q31, 3 |
| Discovery year | 1996-03-12 |
| GenBank acession | U50823 |
| Entrez gene record | 4760 |
| Pubmed identfication | 7754368 8786144 |
| RefSeq identity | NM_002500 |
| Classification | Basic helix-loop-helix proteins |
| Havana BLAST/BLAT | OTTHUMG00000132583 |
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