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NFATC1 Antibody

NFATC1 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenNFATC1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Western blot: 1:1000
NotesTitration of the NFATC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis NFATC1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O95644
PurityAntigen affinity
Description Different isoforms of this protein may regulate inducible expression of different cytokine genes, Five transcript variants encoding distinct isoforms have been identified for this gene, It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A, Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response, The product of this gene is an inducible nuclear component, This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component, The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex
ImmunogenA portion of amino acids 898-927 from the human protein was used as the immunogen for this NFATC1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NFATC1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetNFATC1
Short nameNFATC1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name calcineurin-dependent 1 (Antibody to), cytoplasmic, nuclear factor on activated T-cells
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006816 and calcium ion transport and biological process this GO :0007507 and heart development and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048273 and mitogen-activated protein kinase p38 binding and molecular function, NF-ATC and NFAT2 and NFATc, NFATC1 and IDBG-5452 and ENSG00000131196 and 4772, NFATC1 and IDBG-643394 and ENSBTAG00000000656 and 511224, Nfatc1 and IDBG-161489 and ENSMUSG00000033016 and 18018, calcineurin-dependent 1, cytoplasmic, mitogen-activated protein kinase p38 binding, nuclei, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0001085 and RNA polymerase II transcription factor binding and molecular function this GO :0001205 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005528 and FK506 binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0001085: RNA polymerase II transcription factor binding and also this GO :0001205: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0005528: FK506 binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0048273: mitogen-activated protein kinase p38 binding, this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0001085: RNA polymerase II transcription factor binding, this GO :0001205: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0005528: FK506 binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0048273: mitogen-activated protein kinase p38 binding, nuclear factor of activated T-cells
Identity 7775
Gene NFATC1
Long gene name nuclear factor of activated T-cells 1
Synonyms gene name calcineurin-dependent 1 , cytoplasmic, nuclear factor of activated T-cells
Synonyms NF-ATC NFATc NFAT2
Locus 18q23
Discovery year 1994-11-16
GenBank acession U08015
Entrez gene record 4772
Pubmed identfication 8202141
RefSeq identity NM_172390
Classification Nuclear factors of activated T-cells
Havana BLAST/BLAT OTTHUMG00000132897

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