| Long name | FITC Conjugated, NFATC4 (Ser168 + Ser170) Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NFATC4 Ser168 + Ser170 |
| Specificity | This is a highly specific antibody against NFATC4 Ser168 + Ser170 |
| Modification | Phosphorylation |
| Modification site | Ser168 + Ser170 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human NFATC4 around the phosphorylation site of Ser168 + Ser170 |
| Gene ID number | 4776 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Alternatively spliced transcript variants encodingdifferent isoforms have been noted for this gene, Oct 2008], Theproduct of this gene plays a role in the inducible expression ofcytokine genes in T cells, [provided byRefSeq, especially in the induction of the IL-2and IL-4, Other members of this family of nuclear factors of activated Tcells also participate in the formation of this complex, The product of this gene is a member of the nuclearfactors of activated T cells DNA-binding transcription complex, This complex consists of at least two components: a preexistingcytosolic component that translocates to the nucleus upon T cellreceptor (TCR) stimulation and an inducible nuclear component |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | NFAT3 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | NFATC4 (Ser168 + Ser170) Conjugated |
| Short name | FITC Conjugated, NFATC4 (Ser168 + Ser170) Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | calcineurin-dependent 4 (Ser168 and Ser170) (Antibody to), cytoplasmic, fluorecein coupled, nuclear factor on activated T-cells |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006954 and inflammatory response and biological process this GO :0007507 and heart development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034644 and cellular response to UV and biological process this GO :0042975 and peroxisome proliferator activated receptor binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045111 and intermediate filament cytoskeleton and cellular component this GO :0045333 and cellular respiration and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0055001 and muscle cell development and biological process this GO :0071285 and cellular response to lithium ion and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, NF-AT3 and NF-ATC4 and NFAT3, NFATC4 and IDBG-3927 and ENSG00000100968 and 4776, NFATC4 and IDBG-645671 and ENSBTAG00000006366 and, Nfatc4 and IDBG-166063 and ENSMUSG00000023411 and 73181, calcineurin-dependent 4, cytoplasmic, nuclei, peroxisome proliferator activated receptor binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001569 and patterning of blood vessels and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0042975: peroxisome proliferator activated receptor binding, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003713: transcription coactivator activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0042975: peroxisome proliferator activated receptor binding, nuclear factor of activated T-cells |
| Identity | 7778 |
| Gene | NFATC4 |
| Long gene name | nuclear factor of activated T-cells 4 |
| Synonyms gene name | calcineurin-dependent 4 , cytoplasmic, nuclear factor of activated T-cells |
| Locus | 14q12 |
| Discovery year | 1994-11-16 |
| GenBank acession | BC053855 |
| Entrez gene record | 4776 |
| Pubmed identfication | 7749981 |
| RefSeq identity | NM_004554 |
| Classification | Nuclear factors of activated T-cells |
| Havana BLAST/BLAT | OTTHUMG00000029351 |
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