| Alternative name1 | EC 2, FLJ11330, NAK, NF-kB-activating Kinase, NF-kappa-B-activating Kinase, Serine/threonine Protein Kinase TBK-1, Serine/threonine Protein Kinase TBK1, T, T2K, TANK-binding Kinase 1, 1, 7, 11, Anti-NFkB Activating Kinase (Nuclear Factor kappa B Activating Kinase |
| Alternative name2 | EC 2, FLJ11330, NAK, NF-kB-activating Kinase, NF-kappa-B-activating Kinase, Serine/threonine Protein Kinase TBK-1, Serine/threonine Protein Kinase TBK1, T, T2K, TANK-binding Kinase 1, 1, 7, 11, NFkB Activating Kinase (Nuclear Factor kappa B Activating Kinase |
| Alternative name3 | EC 2, FLJ11330, NAK, NF-kB-activating Kinase, NF-kappa-B-activating Kinase, Serine/threonine Protein Kinase TBK-1, Serine/threonine Protein Kinase TBK1, T, T2K, TANK-binding Kinase 1, 1, 7, 11, NFkB Activating Kinase (Nuclear Factor kappa B Activating Kinase |
| Alternative name4 | NFkB Activating Kinase |
| Alternative name5 | EC 2, FLJ11330, NAK, NF-kB-activating Kinase, NF-kappa-B-activating Kinase, Serine/threonine Protein Kinase TBK-1, Serine/threonine Protein Kinase TBK1, T, T2K, TANK-binding Kinase 1, 1, 7, 11, Anti -NFkB Activating Kinase (Nuclear Factor kappa B Activating Kinase |
| Other names | Breast cancer-associated protein SGA-1M, NEDD4 WW domain-binding protein 5, NEDD4 family-interacting protein 1, NEDD4 family-interacting protein 1, Nedd4 WW domain-binding protein 5, Nedd4 family interacting protein 1, Putative MAPK-activating protein PM13, Putative NF-kappa-B-activating protein 164, Putative NFKB and MAPK-activating protein, breast cancer-associated protein SGA-1M, putative MAPK-activating protein PM13, putative NF-kappa-B-activating protein 164, putative NFKB and MAPK-activating protein, NEDD4 family-interacting protein 1 |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | N4WBP5, N4WBP5, NDFIP1, NDFIP1 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | N/A |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | Other species have not been tested, Reactivity with mouse is likely owing to complete identity between this ortholog and human TBK1 at the site to which the epitope maps, Species Crossreactivity: Reacts with human TBK1, This antibody is specific for human TBK1 |
| Purification method | Affinity Purified by immunoaffinity chromatography |
| Form/Appearance | N/A |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Immunoprecipitation (IP), Western Blot (WB), ELISA (EL/EIA) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | EC 2, FLJ11330, NAK, NF-kB-activating Kinase, NF-kappa-B-activating Kinase, Serine/threonine Protein Kinase TBK-1, Serine/threonine Protein Kinase TBK1, T, T2K, TANK-binding Kinase 1, 1, 7, 11, NFkB Activating Kinase Factor kappa B Activating Kinase |
| Short name | EC 2, FLJ11330, NAK, NF-kB-activating Kinase, NF-kappa-B-activating Kinase, Serine/threonine Protein Kinase TBK-1, Serine/threonine Protein Kinase TBK1, T Antibody, T2K, TANK-binding Kinase 1, 1, 7, 11, NFkB Activating Kinase (Nuclear Factor kappa B Activating Kinase |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | EC 2, FLJ11330, NAK, NF-kB-activating phosphorylation catalyst, NF-kappa-B-activating phosphorylation catalyst, Serine/threonine Protein phosphorylation catalyst TANK-binding kinase 1, Serine/threonine Protein phosphorylation catalyst TBK-1, T (Antibody to), T2K, TANK-binding phosphorylation catalyst 1, 1, 7, 11, NFkB Activating phosphorylation catalyst (Nuclear Factor kappa B Activating phosphorylation catalyst |
| Alternative technique | antibodies |
| Alternative to gene target | Cytoplasm, TBK1 and IDBG-44993 and ENSG00000183735 and 29110, TBK1 and IDBG-634420 and ENSBTAG00000017401 and 533141, Tbk1 and IDBG-192882 and ENSMUSG00000020115 and 56480, this GO :0002218 and activation of innate immune response and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006954 and inflammatory response and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0009615 and response to virus and biological process this GO :0010008 and endosome membrane and cellular component this GO :0010629 and negative regulation of gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016772 and transferase activity, this GO :0003676: nucleic acid binding, this GO :0003676: nucleic acid binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0051219: phosphoprotein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0051219: phosphoprotein binding, transferring phosphorus-containing groups and molecular function this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032606 and type I interferon production and biological process this GO :0032727 and positive regulation of interferon-alpha production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0044565 and dendritic cell proliferation and biological process this GO :0045087 and innate immune response and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0051219 and phosphoprotein binding and molecular function this GO :0051607 and defense response to virus and biological process, TANK-binding kinase 1 |
| Identity | 11562 |
| Gene | TANK |
| Long gene name | TRAF family member associated NFKB activator |
| Synonyms gene | TRAF2 |
| Synonyms gene name | TRAF family member-associated NFKB activator |
| Synonyms | I-TRAF |
| Locus | 2q24, 2 |
| Discovery year | 1997-06-12 |
| GenBank acession | U59863 |
| Entrez gene record | 10010 |
| Pubmed identfication | 8710854 8855313 |
| RefSeq identity | NM_133484 |
| Havana BLAST/BLAT | OTTHUMG00000132037 |
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