| Long name | NFKB1 (Ser927) Primary Polyclonal Antibody |
| Also known as | NFKB1 (Ser927) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | NFKB1 Ser927 |
| Specificity | This is a highly specific antibody against NFKB1 Ser927 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser927 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from rat NF-KappaB p105 around the phosphorylation site of Ser927 |
| Gene ID number | 4790 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Rat |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions, Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth, NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, Sep 2009], The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex, Two transcript variants encoding different isoforms have been found for this gene, [provided by RefSeq, and bacterial or viral products, oxidant-free radicals, ultraviolet irradiation, This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DNA binding factor KBF1, DNA binding factor KBF1 EBP1, DNA binding factor KBF1 EBP1, DNA-binding factor KBF1, EBP 1, EBP-1, EBP1, KBF1, MGC54151, NF kB1, NF kappa B, NF kappabeta, NFKB 1, NFKB p105, NFKB p50, NFKB1, Nuclear factor NF kappa B p105 subunit, Nuclear factor NF kappa B p50 subunit, Nuclear factor NF-kappa-B p50 subunit, Nuclear factor kappa B DNA binding subunit, Nuclear factor of kappa light polypeptide gene enhancer in B cells 1, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p84/NF-kappa-B1 p98, DKFZp686C01211 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | NFKB1 (Ser927) |
| Short name | NFKB1 (Ser927) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | nuclear factor on kappa light polypeptide gene enhancer in B-cells 1 (Ser927) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007165 and signal transduction and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0009617 and response to bacterium and biological process this GO :0010744 and positive regulation of macrophage derived foam cell differentiation and biological process this GO :0010884 and positive regulation of lipid storage and biological process this GO :0010956 and negative regulation of calcidiol 1-monooxygenase activity and biological process this GO :0010957 and negative regulation of vitamin D biosynthetic process and biological process this GO :0031072 and heat shock protein binding and molecular function this GO :0031293 and membrane protein intracellular domain proteolysis and biological process this GO :0032269 and negative regulation of cellular protein metabolic process and biological process this GO :0032375 and negative regulation of cholesterol transport and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0033256 and I-kappaB/NF-kappaB complex and cellular component this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045083 and negative regulation of interleukin-12 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046688 and response to copper ion and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071316 and cellular response to nicotine and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071354 and cellular response to interleukin-6 and biological process this GO :0071375 and cellular response to peptide hormone stimulus and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :1900127 and positive regulation of hyaluronan biosynthetic process and biological process this GO :2000630 and positive regulation of miRNA metabolic process and biological process, EBP-1 and KBF1 and NF-kappa-B and NF-kappaB and NF-kB1 and NFkappaB and NFKB-p105 and NFKB-p50 and p105 and p50, NFKB1 and IDBG-31974 and ENSG00000109320 and 4790, Nfkb1 and IDBG-195445 and ENSMUSG00000028163 and 18033, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000975 and regulatory region DNA binding and molecular function this GO :0000976 and transcription regulatory region sequence-specific DNA binding and molecular function this GO :0001071 and nucleic acid binding transcription factor activity and molecular function this GO :0001818 and negative regulation of cytokine production and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0003677 and DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000975: regulatory region DNA binding, this GO :0000975: regulatory region DNA binding and also this GO :0000976: transcription regulatory region sequence-specific DNA binding and also this GO :0001071: nucleic acid binding transcription factor activity and also this GO :0003677: DNA binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0031072: heat shock protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding, this GO :0000976: transcription regulatory region sequence-specific DNA binding, this GO :0001071: nucleic acid binding transcription factor activity, this GO :0003677: DNA binding, this GO :0003690: double-stranded DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0031072: heat shock protein binding, this GO :0042803: protein homodimerization activity, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, transcription regulatory region DNA binding, 60919 and IDBG-640840 and ENSBTAG00000020270 and 616115, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| Identity | 7794 |
| Gene | NFKB1 |
| Long gene name | nuclear factor kappa B subunit 1 |
| Synonyms gene name | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| Synonyms | KBF1 p105 NFKB-p50 p50 NF-kappaB NFkappaB NF-kB1 |
| Locus | 4q24 |
| Discovery year | 1991-11-14 |
| GenBank acession | M58603 |
| Entrez gene record | 4790 |
| Pubmed identfication | 1992489 |
| RefSeq identity | NM_003998 |
| Classification | Ankyrin repeat domain containing NF-kappa B complex subunits |
| Havana BLAST/BLAT | OTTHUMG00000161080 |
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