| Long name | Cy5, 5 Conjugated, NFKBIA (Tyr42) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NFKBIA Tyr42 |
| Specificity | This is a highly specific antibody against NFKBIA Tyr42 |
| Modification | Phosphorylation |
| Modification site | Tyr42 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human IKB alpha around the phosphorylation site of Tyr42 |
| Gene ID number | 4792 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Aug 2011], Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease, The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses, The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export, [provided by RefSeq, which contain multiple ankrin repeat domains, This gene encodes a member of the NF-kappa-B inhibitor family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | IKBA MAD-3 IkappaBalpha |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | NFKBIA (Tyr42) Conjugated |
| Short name | Conjugated, NFKBIA (Tyr42) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | a (Tyr42) (Antibody to), cyanine 5, 5 coupled, nuclear factor on kappa light polypeptide gene enhancer in B-cells inhibitor |
| Alternative technique | antibodies |
| Alternative to gene target | BIKBA and IDBG-632547 and ENSBTAG00000016683 and 282291, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051059 and NF-kappaB binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070417 and cellular response to cold and biological process this GO :0070427 and nucleotide-binding oli this GO merization domain containing 1 signaling pathway and biological process this GO :0070431 and nucleotide-binding oli this GO merization domain containing 2 signaling pathway and biological process, IKBA and MAD-3 and NFKBI, NF-kappaB binding, NFKBIA and IDBG-4758 and ENSG00000100906 and 4792, Nfkbia and IDBG-140708 and ENSMUSG00000021025 and 18035, alpha, nuclei, this GO :0000060 and protein import into nucleus, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0008139: nuclear localization sequence binding and also this GO :0019899: enzyme binding and also this GO :0031072: heat shock protein binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0032403: protein complex binding and also this GO :0042802: identical protein binding and also this GO :0051059: NF-kappaB binding, this GO :0008134: transcription factor binding, this GO :0008139: nuclear localization sequence binding, this GO :0019899: enzyme binding, this GO :0031072: heat shock protein binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0032403: protein complex binding, this GO :0042802: identical protein binding, this GO :0051059: NF-kappaB binding, translocation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007253 and cytoplasmic sequestering of NF-kappaB and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008139 and nuclear localization sequence binding and molecular function this GO :0010468 and regulation of gene expression and biological process this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0010888 and negative regulation of lipid storage and biological process this GO :0016032 and viral process and biological process this GO :0019899 and enzyme binding and molecular function this GO :0031072 and heat shock protein binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032270 and positive regulation of cellular protein metabolic process and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032495 and response to muramyl dipeptide and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033256 and I-kappaB/NF-kappaB complex and cellular component this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042345 and regulation of NF-kappaB import into nucleus and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042994 and cytoplasmic sequestering of transcription factor and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0045087 and innate immune response and biological process this GO :0045638 and negative regulation of myeloid cell differentiation and biological process this GO :0045746 and negative regulation of Notch signaling pathway and biological process this GO :0045893 and positive regulation of transcription, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor |
| Identity | 7797 |
| Gene | NFKBIA |
| Long gene name | NFKB inhibitor alpha |
| Synonyms gene | NFKBI |
| Synonyms gene name | alpha , nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor |
| Synonyms name | NF-kappa-B inhibitor alpha |
| Locus | 14q13, 2 |
| Discovery year | 1992-02-13 |
| Entrez gene record | 4792 |
| Pubmed identfication | 1829648 |
| RefSeq identity | NM_020529 |
| Classification | Ankyrin repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000140220 |
| Locus Specific Databases | NFKBIAbase: Mutation registry for Autosomal dominant anhidrotic ectodermal dysplasia and T-cell immunodeficiency LRG_89 |
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