Name : NG2 Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN5791512500
| Long name | Cy7 Conjugated, NG2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NG2 |
| Specificity | This is a highly specific antibody against NG2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 1060-1110/2322 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human NG2 |
| Gene ID number | 1464 |
| Swiss Prot | Q6UVK1 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | ACK1 and BCAR1, Binds through its extracellular N-terminus growth factors, Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate, Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins, May activate FAK and ERK1/ERK2 signaling cascades, May also inhibit neurite outgrowth and growth cone collapse during axon regeneration, May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin, May promote retraction fiber formation and cell polarization through Rho GTPase activation, May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties, May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, extracellular matrix proteases modulating their activity, Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | NG2 G16 RING5 RMA1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | NG2 Conjugated |
| Short name | Conjugated, NG2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, NG2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10068 |
| Gene | RNF5 |
| Long gene name | ring finger protein 5 |
| Synonyms gene name | E3 ubiquitin protein ligase , ring finger protein 5 |
| Locus | 6p21, 32 |
| Discovery year | 1997-10-16 |
| GenBank acession | U89336 |
| Entrez gene record | 6048 |
| Pubmed identfication | 9533025 |
| RefSeq identity | NM_006913 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000031093 |