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NGBR/Nogo B receptor Antibody

NGBR/Nogo B receptor Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameNGBR/Nogo B receptor Primary Polyclonal Antibody
Also known asNGBR/Nogo B receptor PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNGBR/Nogo B receptor
SpecificityThis is a highly specific antibody against NGBR/Nogo B receptor
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NGBR/Nogo B receptor
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen -B and -C, Knockdown of NgBR mRNA leads to decreased NPC2 levels, NgBR (Nogo-B receptor), NgBR also enhances Niemann-Pick type C2 protein (NPC2) stabilization, NgBR is involved in the regulation of vascular remodeling and angiogenesis, Nogo exists in three different splice forms, Nogo is expressed by oligodendrocytes but not by Schwann cells and associates primarily with the endoplasmic reticulum, Nogo-A, Through this interaction, also known as nuclear undecaprenyl pyrophosphate synthase 1 homolog, and inhibits the spreading of 3T3 fibroblasts, induces collapse of growth cones of chick dorsal root ganglion cells, is a 293 amino acid single-pass type I membrane protein that acts as a specific receptor for the amino-terminus of Nogo-B, which results in the hallmarks of NPC2 mutation: increased intracellular cholesterol accumulation and a loss of sterol sensing, Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NGBR, NGBR_HUMAN, NUS1, nuclear undecaprenyl pyrophosphate synthase 1 homolog, C6orf68
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetNGBR/Nogo B receptor
Short nameNGBR/Nogo B receptor Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNGBR/Nogo B receptor (Antibody to)
Alternative techniqueantibodies
Identity 21042
Gene NUS1
Long gene name NUS1 dehydrodolichyl diphosphate synthase subunit
Synonyms gene C6orf68
Synonyms gene name cerevisiae) , chromosome 6 open reading frame 68 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S
Synonyms MGC7199 NgBR TANGO14
Synonyms name Nogo-B receptor transport and golgi organization 14 homolog (Drosophila)
Locus 6q22, 1
Discovery year 2003-05-08
GenBank acession BC013026
Entrez gene record 116150
Pubmed identfication 25066056
RefSeq identity NM_138459
Havana BLAST/BLAT OTTHUMG00000015458

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