NHLRC1 Antibody

NHLRC1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	NHLRC1 Primary Polyclonal Antibody
Also known as	NHLRC1 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	NHLRC1
Specificity	This is a highly specific antibody against NHLRC1
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NHLRC1
Gene ID number	378884
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Forty-nine different mutations in NHLRC1 have been shown to cause EPM2, Malin, Malin interacts with and polyubiquitinates Laforin, Malin is expressed in brain, Malin localizes to the endoplasmic reticulum and, Malinâ, One cause of Lafora disease is due to mutations in NHLRC1, Rapid and severe mental deterioration follows, Starch-like, Survival is less than 10 years after onset, a protein also implicated in EPM2, also called Lafora disease, also called NHL repeat-containing protein 1, called Lafora bodies, can be observed in brain, cerebellum, containing 6 NHL repeats and 1 RING-type zinc finger, endoplasmic reticulum-associated polyglucosans, heart, in the nucleus, is a single subunit E3 ubiquitin ligase, is an autosomal recessive disease characterized by grand mal seizures and/or myoclonus at about 15 years of age, liver, liver and heart, medulla, muscle, often with psychotic features, skeletal muscle and pancreas, spinal cord, the gene encoding Malin, to a lesser extent, &euro, &trade, Progressive myoclonic epilepsy type 2 (EPM2), s RING domain is responsible for its ability to mediate ubiquitination
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	EPM2A, EPM2B, MGC119262, MGC119264, Malin, NHL repeat containing 1, NHL repeat containing protein 1, NHL repeat-containing protein 1, NHLC1_HUMAN, NHLRC 1, Nhlrc1, E3 ubiquitin-protein ligase NHLRC1
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	NHLRC1
Short name	NHLRC1 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	NHLRC1 (Antibody to)
Alternative technique	antibodies
Identity	21576
Gene	NHLRC1
Long gene name	NHL repeat containing E3 ubiquitin protein ligase 1
Synonyms gene name	NHL repeat containing 1
Synonyms	bA204B7, 2 EPM2B malin
Synonyms name	epilepsy, progressive myoclonus type 2B
Locus	6p22, 3
Discovery year	2003-10-06
GenBank acession	AY324849
Entrez gene record	378884
Pubmed identfication	12958597
Havana BLAST/BLAT	OTTHUMG00000014315

NHLRC1 Antibody

NHLRC1 Antibody size: 0.1ml 263

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