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Nicastrin Antibody

Nicastrin Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNicastrin Primary Polyclonal Antibody
Also known asNicastrin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNicastrin
SpecificityThis is a highly specific antibody against Nicastrin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range33-83/709
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Nicastrin
Gene ID number23385
Swiss ProtQ92542
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein), Essential subunit of the gamma-secretase complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names KIAA0253, NCSTN, Nicastrin, UNQ1874/PRO4317, ATAG1874
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNicastrin
Short nameNicastrin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNicastrin (Antibody to)
Alternative techniqueantibodies
Identity 17091
Gene NCSTN
Long gene name nicastrin
Synonyms KIAA0253 APH2
Locus 1q23, 2
Discovery year 2005-02-08
GenBank acession AF240468
Entrez gene record 23385
Pubmed identfication 9039502 10993067
RefSeq identity NM_015331
Havana BLAST/BLAT OTTHUMG00000033110
Locus Specific Databases LRG_223

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