Name : Nicastrin Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6903542765
| Long name | ALEXA FLUOR 488 Conjugated, Nicastrin Polyclonal Antibody |
| Also known as | Anti-Nicastrin PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Nicastrin |
| Specificity | This is a highly specific antibody against Nicastrin |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 33-83/709 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Nicastrin |
| Gene ID Number | 23385 |
| Swiss Prot | Q92542 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein), Essential subunit of the gamma-secretase complex |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | KIAA0253 APH2 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Nicastrin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Nicastrin |
| Short name | Nicastrin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Nicastrin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17091 |
| Gene | NCSTN |
| Long gene name | nicastrin |
| Locus | 1q23, 2 |
| Discovery year | 2005-02-08 |
| GenBank acession | AF240468 |
| Entrez gene record | 23385 |
| Pubmed identfication | 9039502 10993067 |
| RefSeq identity | NM_015331 |
| Havana BLAST/BLAT | OTTHUMG00000033110 |
| Locus Specific Databases | LRG_223 |