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NIMP Antibody, Biotin Conjugated

NIMP Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, NIMP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNIMP
SpecificityThis is a highly specific antibody against NIMP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human NIMP/RTN4IP1
Gene ID number84816
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background -B and -C, NIMP (NOGO-interacting mitochondrial protein), NIMP is expressed in mitochondrial-rich tissue such as kidney, Nogo exists in three different splice forms, Nogo is expressed by oligodendrocytes but not by Schwann cells, Nogo-A, There are three isoforms of NIMP that are produced as a result of alternative splicing events, Through interaction with Nogo, also known as RTN4IP1 (Reticulon-4-interacting protein 1), and associates primarily with the endoplasmic reticulum, and inhibits the spreading of 3T3 fibroblasts, heart, induces collapse of growth cones of chick dorsal root ganglion cells, is a 396 amino acid mitochondrial protein that contains a C-terminal oxidoreductaselike domain and numerous sites for phosphorylation, it is likely that NIMP plays a role in Nogo-induced inhibition of neurite growth, skeletal muscle and specific regions within the nervous system, Appears to be a potent inhibitor of regeneration following spinal cord injury, Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms NIMP
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNIMP Conjugated
Short name Conjugated, NIMP Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, NIMP (Antibody to)
Alternative techniqueantibodies
Identity 18647
Gene RTN4IP1
Long gene name reticulon 4 interacting protein 1
Locus 6q21
Discovery year 2002-05-23
GenBank acession AF336861
Entrez gene record 84816
Havana BLAST/BLAT OTTHUMG00000015304

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