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NKG2D Antibody

NKG2D Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNKG2D Primary Polyclonal Antibody
Also known asNKG2D PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNKG2D
SpecificityThis is a highly specific antibody against NKG2D
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range130-170/215
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from rat NKG2D
Gene ID number24934
Swiss ProtO70215
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation, Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins, May play a regulatory role in differentiation and survival of NK cells, Participates in NK cell-mediated bone marrow graft rejection, Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, Signaling involves calcium influx, Stimulates perforin-mediated elimination of ligand-expressing tumor cells, culminating in the expression of TNF-alpha, leading to cytotoxic activity, Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CD314, Killer cell lectin-like receptor subfamily K member 1, Klrk1, NK cell receptor D, NK lectin-like receptor, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKLLR, NKR-P2, Nkrp2, NKG2D
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNKG2D
Short nameNKG2D Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNKG2D (Antibody to)
Alternative techniqueantibodies
Identity 18788
Gene KLRK1
Long gene name killer cell lectin like receptor K1
Synonyms gene D12S2489E
Synonyms gene name DNA segment on chromosome 12 (unique) 2489 expressed sequence killer cell lectin-like receptor subfamily K, member 1
Synonyms NKG2D KLR NKG2-D CD314
Locus 12p13, 2
Discovery year 2003-12-12
GenBank acession AJ001687
Entrez gene record 22914
Pubmed identfication 9683661 2007850
RefSeq identity NM_007360
Classification Killer cell lectin like receptors CD molecules C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000168574

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