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NKG2D Antibody, ALEXA FLUOR 488

NKG2D Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, NKG2D Polyclonal Antibody
Also known asAnti-NKG2D PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNKG2D
SpecificityThis is a highly specific antibody against NKG2D
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range130-170/215
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from rat NKG2D
Gene ID Number24934
Swiss ProtO70215
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation, Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins, May play a regulatory role in differentiation and survival of NK cells, Participates in NK cell-mediated bone marrow graft rejection, Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, Signaling involves calcium influx, Stimulates perforin-mediated elimination of ligand-expressing tumor cells, culminating in the expression of TNF-alpha, leading to cytotoxic activity, Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms NKG2D KLR NKG2-D CD314
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the NKG2D Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetNKG2D
Short nameNKG2D Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, NKG2D (Antibody to)
Alternative techniqueantibodies
Identity 18788
Gene KLRK1
Long gene name killer cell lectin like receptor K1
Synonyms gene D12S2489E
Synonyms gene name DNA segment on chromosome 12 (unique) 2489 expressed sequence killer cell lectin-like receptor subfamily K, member 1
Locus 12p13, 2
Discovery year 2003-12-12
GenBank acession AJ001687
Entrez gene record 22914
Pubmed identfication 9683661 2007850
RefSeq identity NM_007360
Classification Killer cell lectin like receptors CD molecules C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000168574

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