Filters

NKG2D Antibody, FITC Conjugated

NKG2D Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, NKG2D Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNKG2D
SpecificityThis is a highly specific antibody against NKG2D
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range130-170/215
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from rat NKG2D
Gene ID number24934
Swiss ProtO70215
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation, Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins, May play a regulatory role in differentiation and survival of NK cells, Participates in NK cell-mediated bone marrow graft rejection, Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, Signaling involves calcium influx, Stimulates perforin-mediated elimination of ligand-expressing tumor cells, culminating in the expression of TNF-alpha, leading to cytotoxic activity, Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms NKG2D KLR NKG2-D CD314
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNKG2D Conjugated
Short name FITC Conjugated, NKG2D Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, NKG2D (Antibody to)
Alternative techniqueantibodies
Identity 18788
Gene KLRK1
Long gene name killer cell lectin like receptor K1
Synonyms gene D12S2489E
Synonyms gene name DNA segment on chromosome 12 (unique) 2489 expressed sequence killer cell lectin-like receptor subfamily K, member 1
Locus 12p13, 2
Discovery year 2003-12-12
GenBank acession AJ001687
Entrez gene record 22914
Pubmed identfication 9683661 2007850
RefSeq identity NM_007360
Classification Killer cell lectin like receptors CD molecules C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000168574

Similar products

Subscribe to our Newsletter