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NLE1 Antibody, Cy5 Conjugated

NLE1 Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, NLE1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNLE1
SpecificityThis is a highly specific antibody against NLE1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human NLE1
Gene ID number54475
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Deletion of the NLE1 gene in mice during the early stages of development results in embryonic death, In plants, It may also play a role in 60S ribosomal subunit biogenesis in yeast, NLE1 contains eight WD40 domains and produces one isoform due to alternative splicing, NLE1 is a 485 amino acid WD40-repeat protein that binds to the cytoplasmic domain of Notch, NLE1 is crucial for normal cellular growth and development, Notch receptors play an important role in development and cell-fate decisions, Notchless is a loss-of-function mutant allele that encodes for protein NLE1 (notchless homolog 1), Under-expression during shoot proliferation causes pleiotropic defects such as delayed flowering and abnormal organ maturation, regulating its signaling activity in Drosophila melanogaster and in mice, while gene deletion in the late stages of development leads to activation of a caspase-3-dependent apoptotic pathway, The Notch signaling pathway is an evolutionary conserved system that is involved in intracellular communication
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms FLJ10458
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNLE1 Conjugated
Short name Conjugated, NLE1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, NLE1 (Antibody to)
Alternative techniqueantibodies
Identity 19889
Gene NLE1
Long gene name notchless homolog 1
Synonyms gene name notchless homolog 1 (Drosophila)
Synonyms name (Drosophila) , Notchless gene homolog
Locus 17q12
Discovery year 2005-05-24
Entrez gene record 54475
RefSeq identity NM_018096
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000132928

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