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NMDAR2B (Tyr1070) Antibody, Biotin Conjugated

NMDAR2B (Tyr1070) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, NMDAR2B (Tyr1070) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNMDAR2B Tyr1070
Specificity This phosphorylated site is homologous to that of Tyr1070 in Mouse and Rat, This is a highly specific antibody against NMDAR2B Tyr1070
ModificationPhosphorylation
Modification siteTyr1070
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1040-1090/1484
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1070
Gene ID number2904
Swiss ProtQ13224
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background In concert with DAPK1 at extrasynaptic sites, Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, Mediated by glycine, acts as a central mediator for stroke damage, resulting in an irreversible neuronal death (By similarity), NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms GluN2B
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNMDAR2B (Tyr1070) Conjugated
Short name Conjugated, NMDAR2B (Tyr1070) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, NMDAR2B (Tyr1070) (Antibody to)
Alternative techniqueantibodies
Identity 4586
Gene GRIN2B
Long gene name glutamate ionotropic receptor NMDA type subunit 2B
Synonyms gene NMDAR2B
Synonyms gene name N-methyl D-aspartate 2B , glutamate receptor, ionotropic
Locus 12p13, 1
Discovery year 1992-09-18
Entrez gene record 2904
Pubmed identfication 1350383
Classification Glutamate ionotropic receptor NMDA type subunits
Havana BLAST/BLAT OTTHUMG00000137373

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