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NMDAR2B (Tyr1070) Antibody, PE Conjugated

NMDAR2B (Tyr1070) Antibody, PE Conjugated size: 0.1ml 385

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 385
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name PE Conjugated, NMDAR2B (Tyr1070) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationPE
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNMDAR2B Tyr1070
Specificity This phosphorylated site is homologous to that of Tyr1070 in Mouse and Rat, This is a highly specific antibody against NMDAR2B Tyr1070
ModificationPhosphorylation
Modification siteTyr1070
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1040-1090/1484
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1070
Gene ID number2904
Swiss ProtQ13224
Tested applicationsFCM
Recommended dilutionsFCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background In concert with DAPK1 at extrasynaptic sites, Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, Mediated by glycine, acts as a central mediator for stroke damage, resulting in an irreversible neuronal death (By similarity), NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission480, 565nm/578nm
Synonyms GluN2B
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNMDAR2B (Tyr1070) PE Conjugated
Short name PE Conjugated, NMDAR2B (Tyr1070) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelPE
Alternative name peroxidase coupled, NMDAR2B (Tyr1070) (Antibody to)
Alternative techniqueantibodies
Identity 4586
Gene GRIN2B
Long gene name glutamate ionotropic receptor NMDA type subunit 2B
Synonyms gene NMDAR2B
Synonyms gene name N-methyl D-aspartate 2B , glutamate receptor, ionotropic
Locus 12p13, 1
Discovery year 1992-09-18
Entrez gene record 2904
Pubmed identfication 1350383
Classification Glutamate ionotropic receptor NMDA type subunits
Havana BLAST/BLAT OTTHUMG00000137373

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