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NMDAR2B (Tyr1336) Antibody, Cy3 Conjugated

NMDAR2B (Tyr1336) Antibody, Cy3 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, NMDAR2B (Tyr1336) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNMDAR2B Tyr1336
Specificity This phosphorylation site is homologous to that of Tyr1336 in Mouse and Rat, This is a highly specific antibody against NMDAR2B Tyr1336
ModificationPhosphorylation
Modification siteTyr1336
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1310-1360/1484
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1336
Gene ID number2904
Swiss ProtQ13224
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background In concert with DAPK1 at extrasynaptic sites, Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, Mediated by glycine, acts as a central mediator for stroke damage, resulting in an irreversible neuronal death (By similarity), NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms GluN2B
Properties 1 of the NMDAR2B (Tyr1336) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNMDAR2B (Tyr1336) Conjugated
Short name Conjugated, NMDAR2B (Tyr1336) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, NMDAR2B (Tyr1336) (Antibody to)
Alternative techniqueantibodies
Identity 4586
Gene GRIN2B
Long gene name glutamate ionotropic receptor NMDA type subunit 2B
Synonyms gene NMDAR2B
Synonyms gene name N-methyl D-aspartate 2B , glutamate receptor, ionotropic
Locus 12p13, 1
Discovery year 1992-09-18
Entrez gene record 2904
Pubmed identfication 1350383
Classification Glutamate ionotropic receptor NMDA type subunits
Havana BLAST/BLAT OTTHUMG00000137373

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