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NOBOX Antibody

NOBOX Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNOBOX Primary Polyclonal Antibody
Also known asNOBOX PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNOBOX
SpecificityThis is a highly specific antibody against NOBOX
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NOBOX
Gene ID number135935
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 1% of all women are affected by POF, In addition, Missense mutations have been shown to cause nonsyndromic ovarian failure by disrupting the NOBOX proteins ability to bind to NOBOX DNA-binding element (NBE), NOBOX (newborn ovary homeobox gene), NOBOX expression in the ovary is oocyte specific, The cessation of ovarian function under the age of 40 years results in premature ovarian failure (POF) and is accompanied by amenorrhea, an ooctye-specific homeobox gene, and mutations in a few genes, and thereby inhibiting its regulation of Pou5f1 and GDF-9, but it shows expression in adult testis and pancreas as well, hypoestrogenism and elevated serum gonadotropin concentrations, including inhibin? fsh receptor and the LH/choriogonadotropin receptor have been linked to POF, is a critical protein involved in early folliculogenesis, several germ cell specific genes and downstream transcription factors are thought to play and important role in human oogenesis, Early ovarian folliculogenesis is characterized by the breakdown of germ cell clusters and formation of primordial follicles
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NOBOX Oogenesis Homeobox, NOBOX_HUMAN, Nobox, OG-2, OG2, Og2x, POF5, TCAG_12042, Homeobox protein NOBOX
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNOBOX
Short nameNOBOX Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNOBOX (Antibody to)
Alternative techniqueantibodies
Identity 22448
Gene NOBOX
Long gene name NOBOX oogenesis homeobox
Synonyms OG2 Og2x
Synonyms name newborn ovary homeobox-encoding gene
Locus 7q35
Discovery year 2006-05-19
Entrez gene record 135935
Pubmed identfication 11804785 16597639
RefSeq identity XM_001134420
Classification PRD class homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000158051

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