Name : NOBOX Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6078559147
| Long name | ALEXA FLUOR 488 Conjugated, NOBOX Polyclonal Antibody |
| Also known as | Anti-NOBOX PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NOBOX |
| Specificity | This is a highly specific antibody against NOBOX |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NOBOX |
| Gene ID Number | 135935 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | 1% of all women are affected by POF, In addition, Missense mutations have been shown to cause nonsyndromic ovarian failure by disrupting the NOBOX proteins ability to bind to NOBOX DNA-binding element (NBE), NOBOX (newborn ovary homeobox gene), NOBOX expression in the ovary is oocyte specific, The cessation of ovarian function under the age of 40 years results in premature ovarian failure (POF) and is accompanied by amenorrhea, an ooctye-specific homeobox gene, and mutations in a few genes, and thereby inhibiting its regulation of Pou5f1 and GDF-9, but it shows expression in adult testis and pancreas as well, hypoestrogenism and elevated serum gonadotropin concentrations, including inhibin? fsh receptor and the LH/choriogonadotropin receptor have been linked to POF, is a critical protein involved in early folliculogenesis, several germ cell specific genes and downstream transcription factors are thought to play and important role in human oogenesis, Early ovarian folliculogenesis is characterized by the breakdown of germ cell clusters and formation of primordial follicles |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | OG2 Og2x |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the NOBOX Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | NOBOX |
| Short name | NOBOX Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, NOBOX (Antibody to) |
| Alternative technique | antibodies |
| Identity | 22448 |
| Gene | NOBOX |
| Long gene name | NOBOX oogenesis homeobox |
| Synonyms name | newborn ovary homeobox-encoding gene |
| Locus | 7q35 |
| Discovery year | 2006-05-19 |
| Entrez gene record | 135935 |
| Pubmed identfication | 11804785 16597639 |
| RefSeq identity | XM_001134420 |
| Classification | PRD class homeoboxes and pseudogenes |
| Havana BLAST/BLAT | OTTHUMG00000158051 |